Is Otezla safe to take during pregnancy?
For people with plaque psoriasis, psoriatic arthritis, or oral ulcers associated with Behçet’s Disease, Otezla may be a recommended drug treatment option. However, there is insufficient research to determine the safety of Otezla during pregnancy. Animal studies have suggested an increased risk of spontaneous abortion at higher doses but there have been no controlled human trials for pregnant people taking Otezla. As such, pregnant patients are advised to not take Otezla and those planning to become pregnant should also seek alternate treatments that do not involve Otezla use.
If someone takes Otezla and unwittingly becomes pregnant during the course of treatment they can enroll in the pregnancy registry set up by Celgene Corp., which monitors pregnancy outcomes of women exposed to orally-administered treatments with proticosteroid activator therapy or PDE4 inhibitors like Otezla.
Pregnant and require relief from psoriatic arthritis? Learn more about Otezla, its benefits and possible risks when taken during pregnancy in this guide!
Uses of Otezla
Otezla (apremilast) is a prescription medication used to treat adults with active psoriatic arthritis and plaque psoriasis. It is an oral small molecule, which works by inhibiting certain enzymes responsible for inflammation and immunity. Otezla may be prescribed for other uses not listed here. Patients should ask their doctor or pharmacist for additional information about Otezla and any possible side effects associated with taking it as a treatment option. Before taking Otezla, patients should tell their doctor if they have had stomach ulcers in the past or ever have taken any other medications that increased their risk of getting stomach ulcers or intestinal bleeding.
Otezla (apremilast) is a prescription medication used to treat adults with active psoriatic arthritis and plaque psoriasis. It works by inhibiting certain enzymes responsible for inflammation and immunity. Otezla may also be prescribed for other uses not listed here.
Otezla is used to reduce the signs and symptoms of psoriatic arthritis, including joint pain, swelling, and stiffness. It is also used to reduce the redness, itching, and scaling caused by plaque psoriasis.
Side Effects of Otezla
Otezla (apremilast) is an oral medicine prescribed to treat several diseases, including psoriatic arthritis, plaque psoriasis, and moderate to severe Crohn’s disease. As with any medicine there are potential side effects that can be associated with Otezla.
Common side effects of Otezla include diarrhea, nausea, headache, upper respiratory tract infection, vomiting, and nasopharyngitis. Other more serious side effects include depression or worsening symptoms of depression––so patients should notify their doctor if they experience any changes in mood.
When using Otezla it is important to take appropriate safety measures: Keep all other medicines taken in combination with Otezla separate from each other. In the case of side effects that appear when taking Otezla which cause discomfort or does not go away consult with a doctor and discuss ways to manage them. Lastly, individuals using this drug should always report adverse reactions related to the use of Otezla to the FDA.
Otezla Precautions
Otezla (apremilast) is a prescription medication used to treat adults with certain forms of psoriasis and psoriatic arthritis. It is a type of selective phosphodiesterase-4 (PDE4) inhibitor, a class of drugs that helps reduce inflammation in the body, which can help reduce symptoms associated with certain conditions. It does this by blocking certain chemical messengers made by white blood cells that are involved in the inflammatory process.
However, there are several precautions that must be taken when taking Otezla. Patients should be regularly monitored for signs of depression, suicidal thoughts and significant weight loss while on this medication. Additionally, medications that increase the activity of CYP3A4 enzyme such as phenobarbital, phenytoin, rifampin or St John’s wort must not be taken along with Otezla. Pregnant women should also not take this medication as it could cause harm to an unborn baby. Finally, do not take Otezla if you are allergic to it or to any of its ingredients.
Otezla Food Interactions
Otezla is a medication used to treat severe plaque psoriasis, which can cause painful red, scaly and itchy patches of skin. Otezla may interact with other drugs, supplements and even certain types of food. As is the case with any medication, it’s important to familiarize yourself with these potential interactions to avoid serious side effects or complications.
In general, there are no specific foods that should be avoided when taking Otezla. However, some medications do have known food interactions and doctors may advise you to avoid eating those foods while taking those medications. While on Otezla, it’s a good idea to speak with your doctor or pharmacist before taking any other prescription or non-prescription drugs as well as supplements such as vitamins and herbal remedies. Unfortunately, due to the complexity of drug interactions individualized dosing advice has proven difficult in this setting so consulting an expert would be the best course of action.
Otezla and Pregnancy
People who are pregnant or looking to become pregnant should be notified that the U.S. Food and Drug Administration has placed Otezla (apremilast) into Safety Category C. This means that although it has been used in pregnant animals, no well-controlled studies have been done in humans. The potential benefits of taking Otezla may outweigh the potential riskspose to a pregnant mother and her fetus, however it is up to the prescribing doctor and patient to decide if these risks are worth taking.
A pregnancy exposure registry is available for those women who do choose to continue on with treatment while pregnant in order to closely monitor and measure the outcomes of their child’s development and any side effects present in the mother from using Otezla during pregnancy.
It is important to note that Otezla should not be used during breastfeeding as it is unknown if the drug passes into breast milk. Women who are breastfeeding should consult their doctor before taking this medication.
In conclusion, Otezla is a prescription medication used to treat adults with certain forms of psoriasis and psoriatic arthritis. It can interact with other drugs, supplements and certain types of food. Pregnant women should not take Otezla as it has been placed in Safety Category C by the FDA and could cause harm to an unborn baby. Women who are breastfeeding should also consult their doctor before taking this medication.
It is important to note that Otezla should be taken exactly as prescribed by your doctor. Do not take more or less than the recommended dose and do not stop taking it without first consulting your doctor. It may take several weeks before you notice an improvement in your symptoms. If you experience any side effects while taking Otezla, contact your doctor immediately.
It is important to discuss any concerns you may have about taking Otezla with your doctor. They can help you weigh the risks and benefits of taking this medication and determine if it is right for you. Your doctor can also provide advice on how to manage any side effects that may occur while taking Otezla. Additionally, they can provide information on other treatments that may be more suitable for you.
